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Bcr-abl gene

См. также в других словарях:

  • Bcr-Abl tyrosine-kinase inhibitor — Bcr Abl tyrosine kinase inhibitors (TKI) are the first line therapy for most patients with chronic myelogenous leukemia (CML). In more than 90% cases CML is caused by chromosomal abnormality resulting in the formation of a so called Philadelphia… …   Wikipedia

  • Abl gene — The abl gene is associated with chronic myelogenous leukemia (CML). The abl gene is located on the 9th chromosome. In CML, the gene is activated by being translocated within the bcr (breakpoint cluster region) gene on chromosome 22. This new… …   Wikipedia

  • ген Bcr-abl — Ген предрасположенности к раку крови, ответственный за развитие хронической миеломы у людей носителей данного гена [http://www.dunwoodypress.com/148/PDF/Biotech Eng Rus.pdf] Тематики биотехнологии EN Bcr abl gene …   Справочник технического переводчика

  • BCR-Gen — Breakpoint cluster region Größe 1271 aa; 142,8 kDa Struktur Homotetramer Isoformen 2 …   Deutsch Wikipedia

  • BCR Gen — Breakpoint cluster region Größe 1271 aa; 142,8 kDa Struktur Homotetramer Isoformen 2 …   Deutsch Wikipedia

  • BCR gene — The BCR gene is one of the two genes in the bcr abl complex, which is associated with the Philadelphia chromosome.PathologyA reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in… …   Wikipedia

  • C-Abl — Teilstruktur von c Abl mit den Domänen SH2 (türkis), SH3 (blau) und der Kinasedomäne (grün rot) in Komplex mit den Inhibitoren PD166326 und Myristylat basierend auf der Kristallstruktur …   Deutsch Wikipedia

  • HRK (gene) — Harakiri, BCL2 interacting protein (contains only BH3 domain) Identifiers Symbols HRK; DP5; HARAKIRI External IDs …   Wikipedia

  • STS-1 (gene) — Cbl interacting protein Sts 1, also known as STS 1, is a human gene.cite web | title = Entrez Gene: STS 1 Cbl interacting protein Sts 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=84959| accessdate = ]… …   Wikipedia

  • Fusion gene — A fusion gene is a hybrid gene formed from two previously separate genes. It can occur as the result of a translocation, interstitial deletion, or chromosomal inversion. The fusion of two genes is often taken as evidence that these genes have… …   Wikipedia

  • CRK (gene) — CRK is a gene which codes a protein exhibiting the SH2 domain. PBB Summary section title = summary text = This gene encodes a member of an adapter protein family that binds to several tyrosine phosphorylated proteins. The product of this gene has …   Wikipedia

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